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FOCUS ON FLUORINE CHEMISTRY
Fluorine: a special element
Authors: De Maria G.
Fluorine has quite unique properties and is often considered a sort of “magic element”, whose incorporation is able to bring about improvement and important modification
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Fluorine modulated biaryls How does the smallest heteroelement affect atropisomerism
Authors: Leroux F. (ECPM, Strasbourg Cedex, France)
The presence of fluorine in organic molecules is often associated with unexpected properties. This article describes the influence of the smallest heteroelement on the rotational
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Synthesis and synthetic applications of allylic monofluorides
Authors: Pacheco M.C., Gouverneur V. (Univ of Oxford, UK)
This mini-review discusses why allylic monofluorides are important structural motifs and summarises the different methodologies available to date for their preparation. The synthe
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Perfluorodiacyl Peroxides: a class of free radical sources with a wide range of thermal decomposition temperatures
Authors: Corvaja C., Famulari A., Franco L., Galimberti M., Metrangolo P., Navarrini W. (Univ of Padova, Italy), Resnati G., Sansotera M.
Perfluorodiacyl peroxides are an important class of perfluorinated peroxides. Thermal decompositions of selected perfluorinated peroxides have been analyzed in terms of stability
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New trends in the preparation of nitrogen-containing organofluorine compounds
Authors: S. Fustero, Sanz-Cervera J.F.(Univ de Valencia, burjassot, Spain), Flores S., Bueno J., Moscardò J., Blasco R., Albert L.
Nitrogen-containing organofluorine compounds are appealing potentially bioactive substances because of the special properties that the fluorine atom imparts them. However, their p
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Fluorinated pheromones in the insect communication system
Authors: Viani F. (CNR, Milan, Italy), Fossati G., Frigerio M., Maffezzoni R., Moussier N., Volonterio A.
Fluorinated analogues of natural pheromones can interfere in the communication system of the insects. Therefore, they may play a prominent role in the fight against pests in crop
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Fluorine’s unique role in the supramolecular assemblage
Authors: Ono T. (AIST, Nagoya, Japan)
ABSTRACT The fluorine’s effect on the molecular assemblage was discussed. The topics include optical resolution of the enantiomer mixtures of chiral trifluoromethylated compounds
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Fluorous catalysis
Authors: Vincent J.M., Lastecoueres D. (CNRS UMR, Talence Cedex, France)
Among the various strategies developed in recent years to recycle catalysts, fluorous catalysis, based on catalysts bearing perfluoralkyl chains, is emerging as one of the most po
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The trifluoroethylamine function as peptide bond replacement
Authors: Sani M., Sinisi R., Molteni M., Jagodzinska M., Huguenot F., Bruché L., Zanda M. (Politecnico of Milan, Italy)
A new, highly promising strategy in drug discovery, consisting of the replacement of the natural peptide or amide function by a xenobiotic trifluoroethylamine is discussed
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Self-disproportionation of enantiomers on achiral phase chromatography. One more example of fluorine’s magic powers
Authors: Soloshonok V.A., Berbasov D.O. (Univ of Oklahoma, OK, USA)
It is very well known that separation of enantiomers, possessing identical physicochemical properties, required intervention of an external chiral element to provide for formation
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Fluorination of a chiral hydroxy compound at technical scale
Authors: Pleschke A., Dockner M., Schelhaas M., Käsbauer J., Heise K.P., Eymann W., Antons S. (Lanxess, Germany)
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Solvay Solexis: a history of innovation The evolution of Fluorine Chemistry
Authors: Tommasi G., (Solvay Solexis, Italy)
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